KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
19.39
Human Site:
S1104
Identified Species:
30.48
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
S1104
I
E
Y
E
Y
I
N
S
Q
G
S
E
Q
Q
S
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
S1104
I
E
Y
E
Y
I
N
S
Q
G
S
E
Q
Q
S
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
V784
C
D
W
W
S
V
G
V
I
L
F
E
M
L
V
Dog
Lupus familis
XP_534537
1097
121903
A1070
R
C
P
K
P
S
G
A
D
A
S
Q
A
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
S1103
I
E
Y
E
Y
I
H
S
Q
G
S
E
Q
Q
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
S1094
I
E
Y
E
Y
S
S
S
Q
N
S
E
Q
Q
S
Chicken
Gallus gallus
XP_419666
1136
127431
S1110
I
E
Y
E
Y
S
S
S
Q
N
S
E
Q
Q
S
Frog
Xenopus laevis
NP_001087838
1118
125984
S1090
F
R
Y
D
Y
D
D
S
Q
D
T
G
G
K
D
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
E1042
K
P
I
E
S
E
E
E
D
E
D
E
D
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
F1080
D
R
T
F
H
G
F
F
E
F
T
F
R
R
F
Honey Bee
Apis mellifera
XP_395146
1137
124999
F1112
E
F
T
F
R
R
F
F
D
D
G
G
G
P
A
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
K451
R
F
D
G
L
T
Q
K
M
R
Y
S
D
L
K
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
G1173
I
D
I
D
S
S
P
G
P
G
E
M
E
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
A731
M
T
K
Q
G
G
S
A
P
V
K
E
D
L
P
Red Bread Mold
Neurospora crassa
P38679
598
67999
A573
A
R
G
A
A
A
P
A
Q
Q
E
E
S
P
E
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
6.6
6.6
N.A.
93.3
N.A.
N.A.
80
80
26.6
13.3
N.A.
0
0
0
20
P-Site Similarity:
100
100
26.6
33.3
N.A.
100
N.A.
N.A.
86.6
86.6
53.3
13.3
N.A.
33.3
6.6
0
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
7
7
0
20
0
7
0
0
7
0
7
% A
% Cys:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
7
14
0
7
7
0
20
14
7
0
20
0
14
% D
% Glu:
7
34
0
40
0
7
7
7
7
7
14
60
7
7
7
% E
% Phe:
7
14
0
14
0
0
14
14
0
7
7
7
0
0
7
% F
% Gly:
0
0
7
7
7
14
14
7
0
27
7
14
14
0
0
% G
% His:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
40
0
14
0
0
20
0
0
7
0
0
0
0
0
0
% I
% Lys:
7
0
7
7
0
0
0
7
0
0
7
0
0
7
7
% K
% Leu:
0
0
0
0
7
0
0
0
0
7
0
0
0
20
0
% L
% Met:
7
0
0
0
0
0
0
0
7
0
0
7
7
0
0
% M
% Asn:
0
0
0
0
0
0
14
0
0
14
0
0
0
0
0
% N
% Pro:
0
7
7
0
7
0
14
0
14
0
0
0
0
14
7
% P
% Gln:
0
0
0
7
0
0
7
0
47
7
0
7
34
34
0
% Q
% Arg:
14
20
0
0
7
7
0
0
0
7
0
0
7
14
0
% R
% Ser:
0
0
0
0
20
27
20
40
0
0
40
7
7
0
40
% S
% Thr:
0
7
14
0
0
7
0
0
0
0
14
0
0
0
0
% T
% Val:
0
0
0
0
0
7
0
7
0
7
0
0
0
0
14
% V
% Trp:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
40
0
40
0
0
0
0
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _